Prevalence and Genotyping of Torque Teno Virus in HBV/HIV and Chronic HBV Patients in Iran
نویسندگان
چکیده مقاله:
Background: Torque teno virus (TTV) was the first human Anelloviridae detected in a Japanese patient with an unknown type of hepatitis in 1997. TTV is by far the first known single-stranded circular DNA virus infecting human. In spite of its widespread nature in human population, its pathogenesis is still unclear. In addition, information regarding TTV infection in Iranian population is limited. Therefore, we attempted to determine the prevalence and genotype of TTV in three groups: HIV/HBV patients, chronic hepatitis B patients, and healthy individuals. Methods: The presence of TTV DNA in sera was investigated using PCR. The primer sets encompassing two 5΄-UTR and N22 regions were used, and the positive products were collected for sequencing. Phylogenetic tree was generated based on N22 region and using the MEGA 7 software. Results: TTV DNA was detected in 452 patients with HIV/HBV and chronic hepatitis B, as well as in healthy control groups. The results from PCR indicated positive rates ftrated ates positive rates Results, Conclusionffor these three groups, 48%, 54%, and 49.3% using 5΄-UTR primer and 15.1%, 12%, and 8% using N22 primer, respectively. Conclusion: Five genogroups were observed, which the second group was found to be the most frequent. The results of 5΄-UTR primer showed more prevalence of TTV DNA comparing to N22 primer in patients and healthy control.
منابع مشابه
Prevalence of Torque Teno Virus in Healthy Individuals and Peoples Infected with Hepatitis C Virus Living in Yazd, Iran
متن کامل
Frequency of Torque Teno Mini Virus in Hepatitis B and C Patients and Healthy Blood Donors in Isfahan, Iran
Background: Recently, some new viruses have been identified for their association with hepatitis which Torque Teno Mini Virus being among them. The aim of this study was to determine the frequency of Torque Teno Mini Virus in healthy individuals and hepatitis B and C patients in Isfahan, Iran. Materials and Methods: One hundred serum samples of healthy individuals from Isfahan Blood Transfusi...
متن کاملrole of cultural iran in promotion of multilaieralism in central asia and caucasus
cultural iran is a scope that is more extended than the political territories of iran as a political unit. this concept means that cultural geography(mehdi moghanlo-1383-1) of iran is greater than its political geography which, according to history, has a long history extending west-east from kandahar to the euphrates and north-south from the persian gulf to the caucasus including transoxiana a...
15 صفحه اولTorque Teno Virus (TTV) Among β-Thalassemia and Haemodialysis Patients from Mazandaran Province (North of Iran)
Torque Teno virus (TTV) is a transfusion transmitted virus that seems to be involved in several complications such as acute respiratory diseases, liver diseases, AIDS, cancer, and autoimmune reactions. In the present study the frequency of TTV was investigated among β- thalassemia (BT) and haemodialysis (HD) patients (high risk patients for TTV) in Mazandaran province, Iran. DNA was ...
متن کاملec adoption and critical success factors of ec in smes in iran
تجارت الکترونیکی شیوه اجرای مسئولیتها، تقابل با مشتریان و امور معمول عملیاتی در شرکتها را تغییر داده است. تجارت الکترونیکی در عمل تنها خرید و فروش کالاها را از طریق ابزار الکترونیک نمی باشد، بلکه تمام فعالیتهای لازم جهت انجام فرایند فروش را نیز در بر میگیرد. در اواخر دهه 1990 بسیاری از شرکتها فعالیتهای خود را به منظور دستیابی به مشتریان جدید و یا ارائه فرصتهای جدید به مشتریان موجود گسترش دادند...
Torque teno mini virus infection in chronic cervicitis and cervical tumors in Isfahan, Iran.
OBJECTIVES Torque teno mini virus (TTMV) is classified as the Betatorquevirus genus of Anelloviridae. Little is known about the prevalence of TTMV in humans. Worldwide, cervical cancer is the second most common cancer affecting women. This study aimed to estimate the TTMV infection frequency in cervicitis cases and cervical tumors including intraepithelial neoplasia (CIN), squamous cell carcino...
متن کاملمنابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ذخیره در منابع من قبلا به منابع من ذحیره شده{@ msg_add @}
عنوان ژورنال
دوره 22 شماره 5
صفحات 338- 344
تاریخ انتشار 2018-09
با دنبال کردن یک ژورنال هنگامی که شماره جدید این ژورنال منتشر می شود به شما از طریق ایمیل اطلاع داده می شود.
میزبانی شده توسط پلتفرم ابری doprax.com
copyright © 2015-2023